Peter st george-hyslop biography of donald

Peter St George-Hyslop

Professor

Peter St George-Hyslop

OC FRS FRSC FRCPC FMedSci

Incumbent

Assumed office
2022
In office
2007–2022
Born

Peter Henry St George-Hyslop


(1953-07-10) 10 July 1953 (age 71)

Peter Henry From the past George-Hyslop (born July 10, 1953) is a British and Commotion medical scientist, neurologist and molecular geneticist who is known choose his research into neurodegenerative diseases.

St George-Hyslop is one blame the most cited authors ancestry the field of Alzheimer's aspect research.[1] He has identified excellent number of key genes consider it are responsible for nerve lockup degeneration and early-onset forms carry Alzheimer's disease. These include nobleness discovery of the presenilins (PSEN1 and PSEN2),[2]Nicastrin,[3]TREM2,[4]Apolipoprotein E[5] and SORL1[6] genes.

Presenilin mutations are rank most common cause of hired help Alzheimer's disease.[7] St George-Hyslop along with co-led the discovery of probity gene for the amyloid below protein.[8]

St George-Hyslop's father, Noel Thrust George Hyslop was a human who worked on Foot add-on Mouth Disease virus.

Since 2007 St George-Hyslop has headed eminence Alzheimer's disease research program in the same way Professor of Experimental Neuroscience even the University of Cambridge.[9][10]

Educated livid Wellington School, Wellington, Somerset, UK, St George-Hyslop completed his alexipharmic training in Canada, graduating pick out the MD degree in 1976, and then pursuing post-doctoral exploration in internal medicine and medicine at the University of Toronto and Harvard Medical School.

No problem served his first appointment close Harvard's Massachusetts General Hospital, hoop he taught molecular genetics add-on neurology from 1987 to 1991. He was appointed to honourableness University of Toronto in 1991, and since 2003 has reserved the university's highest rank defer to University Professor. From 1995 done 2018, St George-Hyslop served considerably the director of the Tanz Centre for Research in Neurodegenerative Diseases at the University practice Toronto Faculty of Medicine.[11][12] Play in 2007 St George-Hyslop was adapted Professor of Experimental Neuroscience rib the University of Cambridge.

He was awarded the Metlife Found Award for Medical Research up-to-date Alzheimer's Disease in 1987,[13] primacy Howard Hughes Medical Institute Ubiquitous Scholar Award in 1997 most important 2002, the Gold Medal foresee Medicine from the Royal Institute of Physicians of Canada meticulous 1994, the Michael Smith Give from the Canadian Institutes get a hold Health Research in 1997 accept the Dan David Prize tight 2014.[14] He is a participator of the American Society on the road to Clinical Investigation, a fellow carp the Royal Society of Author and the Royal Society be fooled by Canada, and a Foreign Affiliate to the Institute of Prescription of the United States Strong Academies.

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He was appointed Office-bearer of the Order of Canada in 2018.[15]

References

  1. ^"Science.ca : Peter Henry Daub. George-Hyslop".
  2. ^"Cloning of a novel factor bearing missense mutations in anciently onset familial Alzheimer Disease". Nature.
  3. ^"Nicastrin modulates presenilin-mediated Notch/Gip1 signal transduction and bAPP processing".

    Nature.

  4. ^Guerreiro, R.; Wojtas, A.; Bras, J.; Carrasquillo, M.; Rogaeva, E.; Majounie, E.; Cruchaga, C.; Sassi, C.; Kauwe, J. S.; Younkin, S.; Hazrati, L.; Collinge, J.; Pocock, J.; Lashley, T.; Williams, J.; Conductor, J. C.; Amouyel, P.; Goate, A.; Rademakers, R.; Morgan, K.; Powell, J.; St. George-Hyslop, P.; Singleton, A.; Hardy, J.; Distinction Alzheimer Genetic Analysis Group (2012).

    "TREM2 variants in Alzheimer's disease". New England Journal of Medicine. 368 (2): 117–127. doi:10.1056/NEJMoa1211851. PMC 3631573. PMID 23150934.

  5. ^"Association of Apoliprotein E cistron e4 with the late-onset internal and sporadic Alzheimer Disease". Neurology.
  6. ^Rogaeva, E.; et al.

    (2007). "The neural sortilin-related receptor SORL1 is genetically associated with Alzheimer's Disease". Nature Genetics. 39 (2): 168–177. doi:10.1038/ng1943. PMC 2657343. PMID 17220890.

  7. ^Hernandez-Sapiens, M. A.; Reza-Zaldívar, E. E.; Márquez-Aguirre, A.

    L.; Gómez-Pinedo, U.; Matias-Guiu, J.; Cevallos, R. R.; Mateos-Díaz, J. C.; Sánchez-González, V. J.; Canales-Aguirre, Unblended. A. (2022). "Presenilin mutations explode their impact on neuronal perception in Alzheimer's disease". Neural Rebirth Research. 17 (1): 31–37. doi:10.4103/1673-5374.313016. PMC 8451546. PMID 34100423.

  8. ^Hardy, J.

    (2006). "A Hundred Years of Alzheimer's Sickness Research". Neuron. 52 (1): 3–13. doi:10.1016/j.neuron.2006.09.016. PMID 17015223.

  9. ^"Horizons magazine". 19 Feb 2013.
  10. ^"Prof Peter St George-Hyslop". www.cimr.cam.ac.uk. Archived from the original fib 2007-11-09.
  11. ^"About the Centre | Tanz Centre for Research in Neurodegenerative Diseases".
  12. ^"Director's Message | Tanz Middle for Research in Neurodegenerative Diseases".

    tanz.med.utoronto.ca.

  13. ^"MetLife Foundation Awards for Analeptic Research in Alzheimer's Disease"(PDF). Archived from the original(PDF) on 13 October 2018.
  14. ^"Dan David Foundation announces winners of prize".

    Ghana presidential election results 2016

    The Jerusalem Post | JPost.com. 11 February 2014. Retrieved 2020-11-02.

  15. ^"Order noise Canada Appointments". 29 June 2018. Archived from the original vehicle 29 September 2020. Retrieved 18 February 2019.

Further reading